Blennow K, de Leon MJ, Zetterberg H: Alzheimer's disease. Lancet. 2006, 368: 387-403. 10.1016/S0140-6736(06)69113-7.
Article
CAS
PubMed
Google Scholar
Rosenberg GA: Matrix metalloproteinases and their multiple roles in neurodegenerative diseases. Lancet Neurol. 2009, 8: 205-216. 10.1016/S1474-4422(09)70016-X.
Article
CAS
PubMed
Google Scholar
Yong VW, Power C, Forsyth P, Edwards DR: Metalloproteinases in biology and pathology of the nervous system. Nat Rev Neurosci. 2001, 2: 502-511. 10.1038/35081571.
Article
CAS
PubMed
Google Scholar
Miners JS, Baig S, Palmer J, Palmer LE, Kehoe PG, Love S: Abeta-degrading enzymes in Alzheimer's disease. Brain Pathol. 2008, 18: 240-252. 10.1111/j.1750-3639.2008.00132.x.
Article
CAS
PubMed
Google Scholar
Gardner J, Ghorpade A: Tissue inhibitor of metalloproteinase (TIMP)-1: the TIMPed balance of matrix metalloproteinases in the central nervous system. J Neurosci Res. 2003, 74: 801-806. 10.1002/jnr.10835.
Article
CAS
PubMed
Google Scholar
Asahina M, Yoshiyama Y, Hattori T: Expression of matrix metalloproteinase-9 and urinary-type plasminogen activator in Alzheimer's disease brain. Clin Neuropathol. 2001, 20: 60-63.
CAS
PubMed
Google Scholar
Yoshiyama Y, Asahina M, Hattori T: Selective distribution of matrix metalloproteinase-3 (MMP-3) in Alzheimer's disease brain. Acta Neuropathol. 2000, 99: 91-95. 10.1007/PL00007428.
Article
CAS
PubMed
Google Scholar
Backstrom JR, Lim GP, Cullen MJ, Tokes ZA: Matrix metalloproteinase-9 (MMP-9) is synthesized in neurons of the human hippocampus and is capable of degrading the amyloid-beta peptide (1-40). J Neurosci. 1996, 16: 7910-7919.
CAS
PubMed
Google Scholar
Deb S, Gottschall PE: Increased production of matrix metalloproteinases in enriched astrocyte and mixed hippocampal cultures treated with beta-amyloid peptides. J Neurochem. 1996, 66: 1641-1647. 10.1046/j.1471-4159.1996.66041641.x.
Article
CAS
PubMed
Google Scholar
Mizoguchi H, Takuma K, Fukuzaki E, Ibi D, Someya E, Akazawa KH, Alkam T, Tsunekawa H, Mouri A, Noda Y, Nabeshima T, Yamada K: Matrix metalloprotease-9 inhibition improves amyloid beta-mediated cognitive impairment and neurotoxicity in mice. J Pharmacol Exp Ther. 2009, 331: 14-22. 10.1124/jpet.109.154724.
Article
CAS
PubMed
Google Scholar
Reitz C, van Rooij FJ, Soares HD, de Maat MP, Hofman A, Witteman JC, Breteler MM: Matrix metalloproteinase 3 haplotypes and plasma amyloid beta levels: The Rotterdam Study. Neurobiol Aging. 2010, 31: 715-718. 10.1016/j.neurobiolaging.2008.05.033.
Article
CAS
PubMed
Google Scholar
Talamagas AA, Efthimiopoulos S, Tsilibary EC, Figueiredo-Pereira ME, Tzinia AK: Abeta(1-40)-induced secretion of matrix metalloproteinase-9 results in sAPPalpha release by association with cell surface APP. Neurobiol Dis. 2007, 28: 304-315. 10.1016/j.nbd.2007.07.016.
Article
CAS
PubMed
Google Scholar
Yan P, Hu X, Song H, Yin K, Bateman RJ, Cirrito JR, Xiao Q, Hsu FF, Turk JW, Xu J, Hsu CY, Holtzman DM, Lee JM: Matrix metalloproteinase-9 degrades amyloid-beta fibrils in vitro and compact plaques in situ. J Biol Chem. 2006, 281: 24566-24574. 10.1074/jbc.M602440200.
Article
CAS
PubMed
Google Scholar
Blennow K: CSF biomarkers for mild cognitive impairment. J Intern Med. 2004, 256: 224-234. 10.1111/j.1365-2796.2004.01368.x.
Article
CAS
PubMed
Google Scholar
Hansson O, Zetterberg H, Buchhave P, Londos E, Blennow K, Minthon L: Association between CSF biomarkers and incipient Alzheimer's disease in patients with mild cognitive impairment: a follow-up study. Lancet Neurol. 2006, 5: 228-234. 10.1016/S1474-4422(06)70355-6.
Article
CAS
PubMed
Google Scholar
Mattsson N, Zetterberg H, Hansson O, Andreasen N, Parnetti L, Jonsson M, Herukka SK, van der Flier WM, Blankenstein MA, Ewers M, Rich K, Kaiser E, Verbeek M, Tsolaki M, Mulugeta E, Rosén E, Aarsland D, Visser PJ, Schröder J, Marcusson J, de Leon M, Hampel H, Scheltens P, Pirttilä T, Wallin A, Jönhagen ME, Minthon L, Winblad B, Blennow K: CSF biomarkers and incipient Alzheimer disease in patients with mild cognitive impairment. JAMA. 2009, 302: 385-393. 10.1001/jama.2009.1064.
Article
CAS
PubMed
Google Scholar
Shaw LM, Vanderstichele H, Knapik-Czajka M, Clark CM, Aisen PS, Petersen RC, Blennow K, Soares H, Simon A, Lewczuk P, Dean R, Siemers E, Potter W, Lee VM, Trojanowski JQ, Alzheimer's Disease Neuroimaging Initiative: Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects. Ann Neurol. 2009, 65: 403-413. 10.1002/ana.21610.
Article
PubMed Central
CAS
PubMed
Google Scholar
Fagan AM, Roe CM, Xiong C, Mintun MA, Morris JC, Holtzman DM: Cerebrospinal fluid tau/beta-amyloid(42) ratio as a prediction of cognitive decline in nondemented older adults. Arch Neurol. 2007, 64: 343-349. 10.1001/archneur.64.3.noc60123.
Article
PubMed
Google Scholar
Gustafson DR, Skoog I, Rosengren L, Zetterberg H, Blennow K: Cerebrospinal fluid beta-amyloid 1-42 concentration may predict cognitive decline in older women. J Neurol Neurosurg Psychiatry. 2007, 78: 461-464. 10.1136/jnnp.2006.100529.
Article
PubMed Central
PubMed
Google Scholar
Stomrud E, Hansson O, Blennow K, Minthon L, Londos E: Cerebrospinal fluid biomarkers predict decline in subjective cognitive function over 3 years in healthy elderly. Dement Geriatr Cogn Disord. 2007, 24: 118-124. 10.1159/000105017.
Article
CAS
PubMed
Google Scholar
American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders, revised (DSM-IIIR). 1987, Arlington, VA, USA: American Psychiatric Association, 3
Google Scholar
McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM: Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology. 1984, 34: 939-944.
Article
CAS
PubMed
Google Scholar
Petersen RC: Mild cognitive impairment as a diagnostic entity. J Intern Med. 2004, 256: 183-194. 10.1111/j.1365-2796.2004.01388.x.
Article
CAS
PubMed
Google Scholar
Crum RM, Anthony JC, Bassett SS, Folstein MF: Population-based norms for the Mini-Mental State Examination by age and educational level. JAMA. 1993, 269: 2386-2391. 10.1001/jama.269.18.2386.
Article
CAS
PubMed
Google Scholar
Bravo G, Hebert R: Age- and education-specific reference values for the Mini-Mental and modified Mini-Mental State Examinations derived from a non-demented elderly population. Int J Geriatr Psychiatry. 1997, 12: 1008-1018. 10.1002/(SICI)1099-1166(199710)12:10<1008::AID-GPS676>3.0.CO;2-A.
Article
CAS
PubMed
Google Scholar
Huppert FA, Cabelli ST, Matthews FE: Brief cognitive assessment in a UK population sample -- distributional properties and the relationship between the MMSE and an extended mental state examination. BMC Geriatr. 2005, 5: 7-10.1186/1471-2318-5-7.
Article
PubMed Central
PubMed
Google Scholar
Blennow K, Wallin A, Agren H, Spenger C, Siegfried J, Vanmechelen E: Tau protein in cerebrospinal fluid: a biochemical marker for axonal degeneration in Alzheimer disease?. Mol Chem Neuropathol. 1995, 26: 231-245. 10.1007/BF02815140.
Article
CAS
PubMed
Google Scholar
Andreasen N, Hesse C, Davidsson P, Minthon L, Wallin A, Winblad B, Vanderstichele H, Vanmechelen E, Blennow K: Cerebrospinal fluid beta-amyloid(1-42) in Alzheimer disease: differences between early- and late-onset Alzheimer disease and stability during the course of disease. Arch Neurol. 1999, 56: 673-680. 10.1001/archneur.56.6.673.
Article
CAS
PubMed
Google Scholar
Olsson A, Vanderstichele H, Andreasen N, De Meyer G, Wallin A, Holmberg B, Rosengren L, Vanmechelen E, Blennow K: Simultaneous measurement of beta-amyloid(1-42), total tau, and phosphorylated tau (Thr181) in cerebrospinal fluid by the xMAP technology. Clin Chem. 2005, 51: 336-345. 10.1373/clinchem.2004.039347.
Article
CAS
PubMed
Google Scholar
Lorenzl S, Buerger K, Hampel H, Beal MF: Profiles of matrix metalloproteinases and their inhibitors in plasma of patients with dementia. Int Psychogeriatr. 2008, 20: 67-76. 10.1017/S1041610207005790.
Article
PubMed
Google Scholar
Lorenzl S, Albers DS, Relkin N, Ngyuen T, Hilgenberg SL, Chirichigno J, Cudkowicz ME, Beal MF: Increased plasma levels of matrix metalloproteinase-9 in patients with Alzheimer's disease. Neurochem Int. 2003, 43: 191-196. 10.1016/S0197-0186(03)00004-4.
Article
CAS
PubMed
Google Scholar
Helbecque N, Cottel D, Hermant X, Amouyel P: Impact of the matrix metalloproteinase MMP-3 on dementia. Neurobiol Aging. 2007, 28: 1215-1220. 10.1016/j.neurobiolaging.2006.05.030.
Article
CAS
PubMed
Google Scholar
Jourquin J, Tremblay E, Decanis N, Charton G, Hanessian S, Chollet AM, Le Diguardher T, Khrestchatisky M, Rivera S: Neuronal activity-dependent increase of net matrix metalloproteinase activity is associated with MMP-9 neurotoxicity after kainate. Eur J Neurosci. 2003, 18: 1507-1517. 10.1046/j.1460-9568.2003.02876.x.
Article
PubMed
Google Scholar
Skoog I, Davidsson P, Aevarsson O, Vanderstichele H, Vanmechelen E, Blennow K: Cerebrospinal fluid beta-amyloid 42 is reduced before the onset of sporadic dementia: a population-based study in 85-year-olds. Dement Geriatr Cogn Disord. 2003, 15: 169-176. 10.1159/000068478.
Article
CAS
PubMed
Google Scholar
Li G, Sokal I, Quinn JF, Leverenz JB, Brodey M, Schellenberg GD, Kaye JA, Raskind MA, Zhang J, Peskind ER, Montine TJ: CSF tau/Abeta42 ratio for increased risk of mild cognitive impairment: a follow-up study. Neurology. 2007, 69: 631-639. 10.1212/01.wnl.0000267428.62582.aa.
Article
CAS
PubMed
Google Scholar
Jack CR, Knopman DS, Jagust WJ, Shaw LM, Aisen PS, Weiner MW, Petersen RC, Trojanowski JQ: Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade. Lancet Neurol. 2010, 9: 119-128. 10.1016/S1474-4422(09)70299-6.
Article
PubMed Central
CAS
PubMed
Google Scholar
Bruno MA, Mufson EJ, Wuu J, Cuello AC: Increased matrix metalloproteinase 9 activity in mild cognitive impairment. J Neuropathol Exp Neurol. 2009, 68: 1309-1318. 10.1097/NEN.0b013e3181c22569.
Article
PubMed Central
CAS
PubMed
Google Scholar
Braak H, Braak E: Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol. 1991, 82: 239-259. 10.1007/BF00308809.
Article
CAS
PubMed
Google Scholar
The National Institute on Aging and Reagan Institute Working Group on Diagnostic Criteria for the Neuropathological Assessment of Alzheimer's Disease: Consensus recommendations for the postmortem diagnosis of Alzheimer's disease. Neurobiol Aging. 1997, 18: S1-2. 10.1016/S0197-4580(97)00057-2.
Article
Google Scholar
Saarela MS, Lehtimaki T, Rinne JO, Hervonen A, Jylha M, Roytta M, Ahonen JP, Mattila KM: Interaction between matrix metalloproteinase 3 and the epsilon4 allele of apolipoprotein E increases the risk of Alzheimer's disease in Finns. Neurosci Lett. 2004, 367: 336-339. 10.1016/j.neulet.2004.06.027.
Article
CAS
PubMed
Google Scholar