Research
Aims and scope
Alzheimer's Research & Therapy is the major forum for translational research into Alzheimer's disease. An international peer-reviewed journal, it publishes open access basic research with a translational focus, as well as clinical trials, research into drug discovery and development, and epidemiologic studies. The journal also provides reviews, viewpoints, commentaries, debates and reports.
Although the primary focus is Alzheimer's disease, the scope encompasses translational research into other neurodegenerative diseases.
Featured research article: Association between blood pressure and Alzheimer disease measured up to 27 years prior to diagnosis: the HUNT Study
There has been a great deal of interest in the relationship between blood pressure and dementia, driven by conflicting evidence from epidemiological studies. In this study, Gabin et al examine this association, measured up to 27 years prior to dementia diagnosis. They found an inverse association between dementia and systolic blood pressure for individuals over 60 years of age.
Featured review: Stem cell models of Alzheimer’s disease: progress and challenges
In this review, Arber et al. review recent developments into induced pluripotent stem cell technology, which promises to be physiologically relevant in vitro. They discuss the widespread adoption of this technology, and how these models have contributed to a deeper understanding of the molecular mechanisms of Alzheimer's disease. They conclude by proposing new directions for using this technology in research to take advantage of the potential it holds.
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A novel Alzheimer’s disease drug candidate targeting inflammation and fatty acid metabolism
Published on: 14 July 2017
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Long-term cognitive outcome of Alzheimer’s disease and dementia with Lewy bodies: dual disease is worse
Published on: 27 June 2017
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Review
BACE1 inhibitor drugs in clinical trials for Alzheimer’s disease
Published on: 24 December 2014
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Alzheimer’s disease drug-development pipeline: few candidates, frequent failures
Published on: 3 July 2014
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Alzheimer's Disease International news
The World Health Organization (WHO) has unanimously adopted a global plan on dementia at the 70th session of the World Health Assembly in Geneva. The plan follows ten years of advocacy by ADI for a global response to the growing impact of dementia worldwide.
To read more about this global plan, please visit the ADI website here.
Editors-in-Chief
Alzheimer's Research & Therapy is edited by Philip Scheltens, Todd Golde and Doug Galasko. Find the full Editorial Board here.
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