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Table 3 Cerebral Aβ and tau deposition in participants with and without high current blood pressure

From: Synergistic interaction of high blood pressure and cerebral beta-amyloid on tau pathology

Variables

High current SBP (n = 22)

Low current SBP (n = 46)

Regression resultsa

 

β (SE)

p-value

 Global Aβ deposition, mean (SD)

1.354 (0.483)

1.364 (0.360)

−0.079 (0.099)

0.426

 IT tau deposition, mean (SD)

1.449 (0.377)

1.413 (0.210)

0.001 (0.072)

0.984

Variables

High current DBP (n = 12)

Low current DBP (n = 56)

Regression resultsa

 

β (SE)

p-value

 Global Aβ deposition, mean (SD)

1.354 (0.483)

1.364 (0.360)

−0.153 (0.120)

0.206

 IT tau deposition, mean (SD)

1.449 (0.377)

1.413 (0.210)

0.158 (0.085)

0.070

  1. Abbreviations: Aβ β-amyloid, IT inferior temporal, SBP systolic blood pressure, DBP diastolic blood pressure, SE standard error
  2. a Each linear regression model for global Aβ or IT tau deposition included high current SBP (≥ 140 mmHg) or DBP state (≥ 90 mmHg) as a categorical independent variable, after adjusting for age, sex, apolipoprotein E ε4 positivity, and the vascular risk score
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Alzheimer's Research & Therapy

ISSN: 1758-9193