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Table 1 Demographic and clinical characteristics of participants

From: Synergistic interaction of high blood pressure and cerebral beta-amyloid on tau pathology

Characteristics

History of hypertension (n = 34)

No history of hypertension (n = 34)

p-value

Age in years, mean (SD)

72.2 (8.0)

70.7 (6.7)

0.425

Females, (%)

21 (62)

19 (56)

0.622

Education in years, mean (SD)

12.1 (4.2)

11.9 (4.0)

0.906

APOE4 carrier, (%)

7 (21)

5 (15)

0.525

SBP in mmHg, mean (SD)

128.8 (14.9)

124.3 (19.4)

0.281

DBP in mmHg, mean (SD)

78.1 (10.2)

75.0 (11.9)

0.253

Onset age of hypertension in years, mean (SD)

60.6 (8.6)

-

 

Duration of hypertension in years, mean (SD)

11.6 (7.0)

-

 

Treatment with antihypertensive medication, (%)

32 (94)

-

 

Diabetes mellitus, (%)

12 (35)

8 (24)

0.287

Coronary artery diseasea, (%)

4 (12)

1 (3)

0.356

Dyslipidemia, (%)

17 (50)

12 (35)

0.220

Stroke, (%)

1 (3)

0

 

TIA

0

0

 

VRS, mean (SD)

1.00 (0.78)

0.62 (0.78)

0.047

Global WMH volume in mL, mean (SD)

17.53 (15.04)

12.00 (13.00)

0.108

  1. Abbreviations: APOE4 apolipoprotein E ε4, SBP systolic blood pressure, DBP diastolic blood pressure, TIA transient ischemic attack, VRS vascular risk score, WMH white matter hyperintensity
  2. a Fisher’s exact test was used for data comparison; other categorical characteristics were compared using the chi-square test and the continuous characteristics were compared using the independent t-test