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Fig. 2 | Alzheimer's Research & Therapy

Fig. 2

From: ApoJ/Clusterin concentrations are determinants of cerebrospinal fluid cholesterol efflux capacity and reduced levels are associated with Alzheimer’s disease

Fig. 2

Multivariate linear regression of CSF CEC and apolipoproteins CSF. CSF cholesterol efflux capacity was measured in CN (n = 50), MCI (n = 18), and AD (n = 40). Association between ApoA1, ApoE, and ApoJ with both CEC in human microglial and neuronal cells (N9 and SH-SY5Y, respectively). Association between ApoA1 significantly associated with N9 microglial and SH-SY5Yneuronal cell CEC (**P < 8.96e−11 and ***P < 3.244e−06, respectively), ApoJ is significantly associated with N9 microglial and SH-SY5Yneuronal cell CEC (**P < 2.22e−05 and *P < 1.22e−02, respectively). ApoE is not associated with either CEC measurement

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Alzheimer's Research & Therapy

ISSN: 1758-9193