Required n per arm to detect an intervention effect | |||
---|---|---|---|
Intervention effect | Episodic memory | Standard global cognitive composite | Personalized global cognitive composite |
ADNI (N = 140) | |||
20% | 461 | 168 | 123 |
30% | 198 | 69 | 51 |
40% | 109 | 36 | 27 |
A05 (N = 65) | |||
20% | 261 | 279 | 239 |
30% | 114 | 115 | 98 |
40% | 63 | 60 | 52 |