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Table 1 Principal sociodemographic and clinical characteristics of studied subjects: Alzheimer’s disease (AD), behavioural variant frontotemporal dementia (bvFTD), mild cognitive impairment (MCI), psychiatric disorders (Psy), and controls (Con). Values are expressed as mean ± SEM

From: Aquaporin-4 cerebrospinal fluid levels are higher in neurodegenerative dementia: looking at glymphatic system dysregulation

  AD bvFTD MCI Psy Con
Number 48 22 20 13 21
Age (years) 69.8 ± 1.1 70.5 ± 1.5 67.3 ± 1.9 62.8 ± 2.3 70.1 ± 1.1
Gender (M:F) 22:26 10:12 10:10 8:5 15:6
Education (years ± SEM) 10.0 ± 0.6 9.9 ± 1.0 10.1 ± 0.8 13.0 ± 1.2 10.4 ± 0.9
Disease duration (years ± SEM) 3.1 ± 0.3 2.3 ± 0.3 2.7 ± 0.4 5.7 ± 2.7 4.0 ± 0.9
MMSE ± SEM 21.2 ± 0.9 23.1 ± 1.2 25.9 ± 0.5 27.2 ± 0.7 27.4 ± 1.0
Beta-amyloid (pg/ml ± SEM) 397.6 ± 20.9 586.3 ± 47.6 760.7 ± 69.6 844.9 ± 124.2 805.2 ± 72.8
Total tau (pg/ml ± SEM) 909.8 ± 72.8 552.2 ± 83.7 306.8 ± 29.1 253.0 ± 31.8 312.1 ± 25.7
P-Tau (pg/ml ± SEM) 149.6 ± 11.3 76.2 ± 13.8 42.3 ± 4.4 36.3 ± 5.8 48.3 ± 5.0
AQP4 (pg/ml ± SEM) 350.4 ± 32.7 310.5 ± 34.6 266.2 ± 25.0 261.6 ± 32.1 209.6 ± 23.4
  1. MMSE Mini-Mental State Examination, AQP4 Aquaporin 4