Fig. 3
![Fig. 3](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fs13195-022-01077-6/MediaObjects/13195_2022_1077_Fig3_HTML.png)
Box plots representing cerebrospinal fluid (CSF) aquaporin 4 (AQP4) levels in the three parameters of ATN classification: A + / − (according to β amyloid CSF levels) on the left, T + / − (according to P-Tau CSF levels) in the middle, and N + / − (according to total Tau levels) on the right. The only significant difference is in the levels of AQP4 in N+ compared to N−