Left/language variant Alzheimer's disease. A 50 year old man presenting with short-term memory loss and significant aphasia, which progressed rapidly over the next few years. Axial T1 MRI at the level of the basal ganglia (left) demonstrated subtly greater left parietal atrophy and expansion of the lateral ventricle (white arrows). Single-photon emission computed tomography (SPECT) done at the same time (right) demonstrated left parietal hypoperfusion (red arrow). The patient died 8 years after symptom onset, and autopsy confirmed Alzheimer's disease (Braak V/VI).