Corder EH, Saunders AM, Strittmatter WJ, Schmechel DE, Gaskell PC, Small GW, Roses AD, Haines JL, Pericak-Vance MA: Gene dose of apolipoprotein E type 4 allele and the risk of AD in late onset families. Science. 1993, 261: 921-923. 10.1126/science.8346443.
Article
CAS
PubMed
Google Scholar
Petersen RC, Smith GE, Ivnik RJ, Tangalos EG, Schaid DJ, Thibodeau SN, Kokmen E, Waring SC, Kurland LT: Apolipoprotein E status as a predictor of the development of Alzheimer's disease in memory-impaired individuals. JAMA. 1995, 273: 1274-1278. 10.1001/jama.1995.03520400044042.
Article
CAS
PubMed
Google Scholar
Caselli RJ, Dueck AC, Osborne D, Sabbagh MN, Connor DJ, Ahern GL, Baxter LC, Rapcsak SZ, Shi J, Woodruff BK, Locke DE, Snyder CH, Alexander GE, Rademakers R, Reiman EM: Longitudinal modeling of age-related memory decline and the APOE epsilon4 effect. N Engl J Med. 2009, 361: 255-263. 10.1056/NEJMoa0809437.
Article
PubMed Central
CAS
PubMed
Google Scholar
van der Flier WM, Pijnenburg YAL, Fox NC, Scheltens P: Early-onset versus late-onset Alzheimer's disease: the case of the missing APOE e4 allele. Lancet Neurol. 2011, 10: 280-288. 10.1016/S1474-4422(10)70306-9.
Article
CAS
PubMed
Google Scholar
Welsh-Bohmer KA, Gearing M, Saunders AM, Roses AD, Mirra S: Apolipoprotein E genotypes in a neuropathological series from the Consortium to Establish a Registry for Alzheimer's Disease. Ann Neurol. 1997, 42: 319-325. 10.1002/ana.410420308.
Article
CAS
PubMed
Google Scholar
Berlau DJ, Corrada MM, Head E, Kawas CH: APOE e2 is associated with intact cognition but increased Alzheimer pathology in the oldest old. Neurology. 2009, 72: 829-834. 10.1212/01.wnl.0000343853.00346.a4.
Article
PubMed Central
CAS
PubMed
Google Scholar
Greenberg SM, Rebeck GW, Vonsattel JP, Gomez-Isla T, Hyman BT: Apolipoprotein E epsilon 4 and cerebral hemorrhage associated with amyloid angiopathy. Ann Neurol. 1995, 38: 254-259. 10.1002/ana.410380219.
Article
CAS
PubMed
Google Scholar
Murray ME, Graff-Radford NR, Ross OA, Petersen RC, Duara R, Dickson DW: Neuropathologically defined subtypes of Alzheimer's disease with distinct clinical characteristics: a retrospective study. Lancet Neurol. 2011, 10: 785-796. 10.1016/S1474-4422(11)70156-9.
Article
PubMed Central
PubMed
Google Scholar
Whitehair DC, Sherzai A, Emond J, Raman R, Aisen PS, Petersen RC, Fleisher AS, Alzheimer's Disease Cooperative Study: Influence of apolipoprotein E varepsilon4 on rates of cognitive and functional decline in mild cognitive impairment. Alzheimers Dement. 2010, 6: 412-419. 10.1016/j.jalz.2009.12.003.
Article
PubMed Central
CAS
PubMed
Google Scholar
Poirer J, Delisle MC, Quirion R, Aubert I, Farlow M, Lahiri M, Hui S, Bertrand P, Nalbantoglu J, Gilfix BM, Gauthier S: Apolipoprotein E4 allele as a predictor of cholinergic deficits and treatment outcome in Alzheimer disease. Proc Natl Acad Sci USA. 1995, 92: 12260-12264. 10.1073/pnas.92.26.12260.
Article
Google Scholar
Orgogozo JM, Gilman S, Dartigues JF, Laurent B, Puel M, Kirby LC, Jouanny P, Dubois B, Eisner L, Flitman S, Michel BF, Boada M, Frank A, Hock C: Subacute meningoencephalitis in a subset of patients with AD after AB42 immunization. Neurology. 2003, 61: 46-54. 10.1212/01.WNL.0000073623.84147.A8.
Article
CAS
PubMed
Google Scholar
Holmes C, Boche D, Wilkinson D, Yadegarfar G, Hopkins V, Bayer A, Jones RW, Bullock R, Love S, Neal JW, Zotova E, Nicoll JA: Long-term effects of AB42 immunisation in Alzheimer's disease: follow-up of a randomized, placebo-controlled phase 1 trial. Lancet. 2008, 372: 216-223. 10.1016/S0140-6736(08)61075-2.
Article
CAS
PubMed
Google Scholar
Boche D, Zotova E, Weller RO, Love S, Neal JW, Pickering RM, Wilkinson D, Holmes C, Nicoll JAR: Consequence of AB immunization on the vasculature of human Alzheimer's disease brain. Brain. 2008, 131: 3299-3310. 10.1093/brain/awn261.
Article
CAS
PubMed
Google Scholar
Sperling R, Salloway S, Brooks DJ, Tampieri D, Barakos J, Fox NC, Raskind M, Sabbagh M, Honig LS, Posteinsson AP, Leiberburg I, Arrighi HM, Morris KA, Lu Y, Liu E, Gregg KM, Brashear HR, Kinney GG, Black R, Grundman M: Amyloid-related imaging abnormalities in patients with Alzheimer's disease treated with bapineuzumab: a retrospective analysis. Lancet Neurol. 2012, 11: 241-249. 10.1016/S1474-4422(12)70015-7.
Article
PubMed Central
CAS
PubMed
Google Scholar
Rinne JO, Brooks DJ, Rossor MN, Fox NC, Bullock R, Klunk WE, Mathis CA, Blennow K, Barakos J, Okello AA, de Llano SRM, Liu E, Koller M, Gregg KM, Schenk D, Black R, Grundman M: 11C-PiB PET assessment of change in fibrillar amyloid-B load in patients with Alzheimer's disease treated with bapineuzumab: a phase 2, double blind, placebo-controlled, ascending dose study. Lancet Neurol. 2010, 9: 363-372. 10.1016/S1474-4422(10)70043-0.
Article
CAS
PubMed
Google Scholar