Fig. 3From: Utilization of fluid-based biomarkers as endpoints in disease-modifying clinical trials for Alzheimer’s disease: a systematic reviewNumber of trials with and without a fluid-based target engagement marker, by target class. Total number of trials (N = 272) was included in this analysis, darker shade indicates use of a fluid-based target engagement marker. Between brackets the total number of trials in that target class is listedBack to article page