Multi-omics and pathway analyses of genome-wide associations implicate regulation and immunity in verbal declarative memory performance

Table 1 Significant tissue-specific correlation between GWAS associations and gene expression

Tissue	Summary gene result	WL-dr			PAR-dr
Tissue	Summary gene result	OR	95% CI	Permutation-adjusted p-value	OR	95% CI	Permutation adjusted p-value
Brain anterior cingulate cortex	Discovery	0.75	[0.64,0.87]	0.005	1.00	[0.88,1.15]	1.000
Brain anterior cingulate cortex	Joint	0.86	[0.75,0.99]	0.399	0.96	[0.84,1.10]	1.00
Brain caudate	Discovery	0.78	[0.68,0.91]	0.026	1.03	[0.90,1.17]	1.000
Brain caudate	Joint	0.91	[0.79,1.04]	0.897	0.98	[0.86,1.12]	1.000
Brain hippocampus	Discovery	0.80	[0.69,0.92]	0.046	0.99	[0.87,1.13]	1.000
Brain hippocampus	Joint	0.89	[0.77,1.02]	0.725	0.93	[0.81,1.07]	0.997
Pituitary	Discovery	0.90	[0.78,1.03]	0.838	0.93	[0.81,1.07]	0.998
Pituitary	Joint	0.78	[0.68,0.90]	0.021	0.85	[0.74, 0.98]	0.350

ISSN: 1758-9193