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Fig. 2 | Alzheimer's Research & Therapy

Fig. 2

From: The fluorescent ligand bTVBT2 reveals increased p-tau uptake by retinal microglia in Alzheimer’s disease patients and AppNL−F/NL−F mice

Fig. 2

bTVBT2 co-localization with tau in human hippocampus. Cornu ammonis 1 (CA1) from an AD case stained against tau (A), bTVBT2 (B), and merged image (C), showing little (long arrows) or no (short arrows) co-localization of bTVBT2 with PHF-1-positive NFTs. Hippocampal sections stained with bTVBT2 together with tau (D), p-tau181 (E), AT8 (F), and PHF-1 (G) showing co-localization of bTVBT2 with tau-positive dystrophic neurites. Scale bars in A–C and D–G represent 10 µm and 20 µm, respectively

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Alzheimer's Research & Therapy

ISSN: 1758-9193