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Table 4 Partial correlations of WM integrity metrics with amyloid deposition. Pearson’s partial correlations between average [11C]PiB-PET SUVR in the medial temporal lobe (MTL) and DTI indices in the left and right CBH. Significance is determined at the Bonferroni-adjusted p-value of 0.00625 and all partial correlations in this table are controlled for age, sex, and APOE ε4 allele positivity. All associations indicated by asterisk (*) were significant (p < 0.001) with small to medium effect sizes

From: White matter integrity is associated with cognition and amyloid burden in older adult Koreans along the Alzheimer’s disease continuum

 

Left cingulum bundle of the hippocampus

Right cingulum bundle of the hippocampus

r

p

r

p

FA

 − 0.267

 < 0.001*

 − 0.233

 < 0.001*

RD

0.330

 < 0.001*

0.325

 < 0.001*

AxD

0.240

 < 0.001*

0.279

 < 0.001*

MD

0.323

 < 0.001*

0.323

 < 0.001*