Fig. 2
Estimated marginal mean SUVR values per group (CN, MCI, AD) of the medial temporal lobe, which includes the Papez circuit, cingulum bundle of the hippocampus (CBH) as well as other circuits relevant to AD. All three groups demonstrate significantly different average SUVR values after controlling for age, sex, and APOE e4 allele positivity (F(2,499) = 71.104, p < 0.001, ηp2 = 0.222), with error bars representing 95% confidence interval. As seen in DTI values, participants with MCI demonstrate an intermediate SUVR uptake that is significantly higher than CN, but less than AD participants