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Fig. 3 | Alzheimer's Research & Therapy

Fig. 3

From: Digital Clock and Recall is superior to the Mini-Mental State Examination for the detection of mild cognitive impairment and mild dementia

Fig. 3

A AUCs for 200 iterations of the binary mild cognitive impairment (MCI) and mild/early dementia classification models. On each iteration, we randomly split the data into train/test sets using the same distribution matching and upsampling procedure. For each split, we then fitted the DCR and MMSE models as before and stored the resulting AUC. On average, the AUC for the DCR-based model (median = 0.70, SD = 0.03) was significantly greater than that for the MMSE (median = 0.63, SD = 0.02; paired permutation p < 0.0001) and was as good as the model inclusing all the sources of information (median = 0.7, SD = 0.032) including the DCR, the MMSE, and demographics. The dashed line represents 50% (chance level) classification accuracy. B The DCR took significantly less time to administer regardless of cohort (log-normal regression, p < 0.0001) and was less variable (DCR SD = 0.53; MMSE SD = 2.43)

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Alzheimer's Research & Therapy

ISSN: 1758-9193