Exploring shared neural substrates underlying cognition and gait variability in adults without dementia

Table 1 Characteristics of participants (N = 207)

	All (N = 207)	Male (N = 113)	Female (N = 94)	p*
Age at *MRI (years)	72.7 ± 6.7	73.0 ± 6.9	72.2 ± 6.5	0.375
Education (years)	13.0 ± 4.1	14.6 ± 3.7	11.0 ± 3.8	< 0.001
Leg length (cm)	84.2 ± 6.7	86.7 ± 6.8	81.3 ± 5.2	< 0.001
Gait variability (ln % CV^†)	0.9 ± 0.3	0.9 ± 0.3	0.9 ± 0.2	0.313
^‡GDS (points)	7.9 ± 5.7	6.5 ± 5.3	9.6 ± 5.7	< 0.001
^§CIRS (points)	7.1 ± 3.3	7.2 ± 3.6	6.9 ± 2.8	0.575
^¶MHIS (points)	0.8 ± 1.2	0.9 ± 1.4	0.7 ± 0.8	0.283
Existence of arthritis (%)	29.0	15.0	45.7	< 0.001
^#CERAD-TS (points)	76.8 ± 10.9	78.2 ± 9.2	75.1 ± 12.5	0.047
**VMS (points)	21.7 ± 4.1	21.8 ± 4	21.7 ± 4.3	0.859

*MRI Magnetic resonance imaging, ^†CV Coefficient of variance, ^‡GDS Geriatric Depression Scale, ^§CIRS Cumulative Illness Rating Scale, ^¶MHIS Modified Hachinski Ischemic Score, ^#CERAD-TS Consortium to Establish a Registry for Alzheimer’s Disease Assessment Packet Neuropsychological Assessment Battery total score, **VMS Verbal Memory Score
*Student’s t-test was performed for continuous variables (presented as mean ± standard deviation) and the chi-square test for categorical variables (presented as %)
^†Natural log transformation of %CV of step time was used as gait variability since %CV of step time was not normally distributed

ISSN: 1758-9193