Fig. 5
From: Whole-brain modeling of the differential influences of amyloid-beta and tau in Alzheimer’s disease
Comparison between the homogeneous model, the optimum result obtained with the heterogeneous model (optim), and the same parameter values but with shuffled burdens. As can be seen, the differences in fit statistics between models are significant. In particular, for the AD cohort, the median phFCD correlation between model and data showed \(r<0.1\) for the heterogeneous model, and \(r\approx 0.2\) for the BEI model. In all subject groups, the difference between these two models is clear, with \(p<0.0005\)