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Fig. 4 | Alzheimer's Research & Therapy

Fig. 4

From: Clinical and biological relevance of glial fibrillary acidic protein in Alzheimer’s disease

Fig. 4

Correlation analysis of blood-based markers in the ATN framework for GFAP, ptau-181, and NfL from top to bottom. AV45 composite SUVR, ptau-181, and hippocampal volume were used as the A, T, and N marker, respectively. The red dots indicate amyloid positive participants and blue circles indicate amyloid negative participants. The linear fitting curves with 95% confidence interval were also shown in the figure. Since ptau-181 itself was treated as the T marker, the correlation between ptau-181 and T marker was meaningless and thus marked as not applicable (N.A.) in the figure. Spearman’s correlation was used for AV45 due to its non-normality and Pearson’s correlation was used for all other measures

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