Divergent brain regional atrophy and associated fiber disruption in amnestic and non-amnestic MCI

Table 2 Correlations between gray matter volume, fiber bundle number, and cognitive tests

	Gray matter volume		Fiber bundle number
	Left hippocampus	Triangular part of right inferior frontal gyrus	Left hippocampus	Triangular part of right inferior frontal gyrus
MMSE	0.240^*	0.140	0.100	0.052
Memory
AVLT delay	0.305^**	0.015	− 0.097	− 0.078
AVLT total	0.303^**	0.017	− 0.060	− 0.009
R-O delay	0.274^**	0.068	− 0.017	0.084
Visual ability
R-O copy	0.022	0.198^*	0.028	0.186^*
CDT	0.005	0.074	0.113	0.140
Language
CVFT	0.197^*	0.112	0.086	0.080
BNT	0.281^**	0.240^*	0.143	0.125
Attention
SDMT	0.157	0.222^*	0.054	0.331^**
TMTA	− 0.060	− 0.181^*	− 0.059	− 0.286^**
Execution
StroopCtime	− 0.155	− 0.242^*	− 0.162	− 0.196^*
TMTB	− 0.101	− 0.195^*	0.003	− 0.282^**

MMSE Mini Mental Status Examination, AVLT Auditory Verbal Learning Test, R-O Rey-Osterrieth Complex Figure; CDT, Clock Drawing Test, CVFT Category Verbal Fluency Test, BNT Boston Naming Test, SDMT Symbol Digit Modalities Test, TMT Trail Making Test, StroopCtime, Time of Stroop Word Color Test C
^*p < 0.05; **p < 0.001. Analyses were controlled for gender, education and age

ISSN: 1758-9193