Table 1 The demographic characteristics for AD group and control group patients

Age (years)

62.53 ± 9.68

58.25 ± 8.88

65.96 ± 9.04

0.006*

Sex, n (%) Female

26 (57.78%)

11 (55.00%)

15 (60.00%)

0.739

Education (years)

12.00 ± 3.84

12.25 ± 3.45

11.80 ± 4.18

0.847

PiB PET-CT, n (%) (positive)

25 (55.6%)

0 (0.00%)

25 (100%)

 < 0.001*

CDR Global Score

0.71 ± 0.87

0.00 ± 0.00

1.28 ± 0.79

 < 0.001*

Blood biomarkers

 PACAP

5.51 ± 2.06

7.46 ± 1.41

3.94 ± 0.70

 < 0.001*

 MAP1LC3B

0.063 ± 0.054

0.087 ± 0.067

0.043 ± 0.028

0.003*

 Aβ42

10.26 ± 3.18

11.71 ± 3.69

9.38 ± 2.52

0.028*

 pTau

4.91 ± 2.71

3.51 ± 2.09

5.82 ± 2.72

0.004*

 Tau

3.44 ± 1.57

3.30 ± 1.57

3.62 ± 1.60

0.552