Fig. 6

Gene set enrichment analysis (GSEA) based on proteomics data of ACAs from the control and advanced AD groups. The horizontal axis shows the enrichment score for each gene set. The enrichment score reflects the degree to which a given gene set is overrepresented in a ranked gene list. The proportion of false positives is controlled by calculating the false discovery rate (FDR) for each normalized enrichment score. The bar length equals normalized enrichment score and the direction indicates the direction of the enriched category association. ^*Gene sets that are significantly different between the AD and control groups with FDR < 0.05