Fig. 3

Diagnostic panel constructed by LASSO model. A LASSO model for variable selection in the AD-CN group. B Boxplot of the included diagnostic proteins for AD diagnosis. C LASSO model for variable selection in the MCI-CN group. D Boxplot of the included diagnostic proteins for MCI diagnosis. *p < 0.05; **p < 0.01. DDC, dopa decarboxylase; CTSC, cathepsin C; EHD4, EH domain containing 4; GSTA3, glutathione S-transferase alpha 3; SLC44A4, solute carrier family 44 member 4; GNS, glucosamine (N-acetyl)-6-sulfatase; GSTA1, glutathione S-transferase alpha 1; ANXA4, annexin A4; PLD3, phospholipase D family member 3; CTSH, cathepsin H; HP, haptoglobin; RPS3, ribosomal protein S3; CPVL, carboxypeptidase vitellogenic like; TUBB, tubulin beta class I; SUCLG2, succinate-CoA ligase GDP-forming subunit beta; PROCR, protein C receptor; TCP1, T-complex 1; ACE, angiotensin I-converting enzyme; FLOT2, flotillin 2; PROZ, protein Z, vitamin K-dependent plasma glycoprotein; C9, complement C9; SERPINA3, serpin family A member 3