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Fig. 4 | Alzheimer's Research & Therapy

Fig. 4

From: Long-term normalization of calcineurin activity in model mice rescues Pin1 and attenuates Alzheimer’s phenotypes without blocking peripheral T cell IL-2 response

Fig. 4

FK506 normalizes chronic cytokine production in the cortex of APP/PS1 mice. Mesoscale multiplex analysis of cytokine levels in the cortex. A IFNγ, B IL-6, C IL-5, D IL-10, E IL12p70, F IL-4, G IL-1β, H TNF-α, I KC/GRO, J IL-2. N = 3 mice per group. * = p < 0.05 by one-way ANOVA with Tukey. For all graphs, WT (blue), WT + FK506 (green), APP/PS1 (red), and APP/PS1 + FK506 (purple)

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Alzheimer's Research & Therapy

ISSN: 1758-9193