Table 1 Clinical and demographic characteristics of participants

Age at scan, mean (SD)

77.1 (6.2)

80.3 (9.7)

75.5 (6.8)

Women, N (%)

3 (37.5)

1 (11.1)

10 (38.5)

Education, mean (SD) years

15.4 (3.1)

16.1 (2.7)

15.8 (2.7)

APOE ε4 carriers (%)

2 (25)

3 (33.3)

19 (73.1) ^a,b

MMSE, mean (SD)

28.7 (1.2)

26.1 (2.8)

21.9 (4.6) ^a,b

GDS, mean (SD)

0.9 (0.9)

3.6 (3.9)

2.9 (3.2)

Global CDR®, mean (SD)

0.0 (0)

0.8 (0.5) ^a

1.0 (0.4) ^a

CDR-SB, mean (SD)

0.0 (0)

3.8 (3.2) ^a

5.7 (2.2) ^a,b

MRI scan/autopsy interval, mean (SD) days

1508.6 (967.6)

1368.2 (879.9)

1531.9 (884.3)

Diagnostic changes by 36 months

3 (to MCI)

8 (to AD)

0