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Table 1 Characteristics of the total population between 18 and 65 years of age in Region Stockholm by presence of chronic stress-induced exhaustion (SED), depression (DEP), or both as well as referents without registered diagnoses of SED or DEP

From: Stress, depression, and risk of dementia – a cohort study in the total population between 18 and 65 years old in Region Stockholm

 

All (n = 1 362 548)

Women (n = 665 997)

Men (n = 696 551)

SED

DEP

SED + DEP

No SED/ DEP

SED

DEP

SED + DEP

No SED/ DEP

SED

DEP

SED + DEP

No SED/ DEP

Baseline (2012–2013)

n (% of the total study population)

4 346 (0.3)

40 101

(2.9)

1 898 (0.1)

1 316 203 (96.6)

3 368 (0.5)

25 854 (3.9)

1497 (0.2)

635 278 (95.4)

978 (0.1)

14 247 (2.0)

401 (0.1)

680 925 (97.8)

Age years mean

(median)

42.05

(42.00)

38.60

(38.00)

41.74

(41.00)

39.69

(39.00)

42.10

(42.00)

38.44

(37.00)

41.63

(41.00)

39.74

(39.00)

41.90

(42.00)

38.90

(38.00)

42.16

(42.00)

39.65

(39.00)

Diagnoses (2014–2022)

Alzheimer disease,a

n (%)

Age years mean

(median)

(range)

14

(0.32)

57.29

(57.00)

(52–64)

148

(0.37)

60.09

(62.00)

(39–65)

9

(0.47)

54.89

(55.00)

(40–61)

2 557

(0.19)

60.38

(62.00)

(29–65)

13

103

8

1 438

1

45

1

1 119

Other dementia,a

n (%)

Age years mean

(median)

(range)

5

(0.12)

56.60

(57.00)

(51–62)

160

(0.40)

58.13

(60.00)

(21–65)

3

(0.16)

57.00

(58.00)

(53–60)

2 654

(0.20)

59.38

(61.00)

(18–65)

4

81

3

1 093

1

79

0

1 561

Mild cognitive disorder,c n (%)

Age years mean

(median)

(range)

36

(0.83)

52.89

(54.50)

(37–63)

528

(1.32)

54.02

57.00

(18–65)

31

(1.63)

48.26

50.00

(22–61)

6 754

(0.51)

56.13

60.00

(18–65)

32

327

24

3 273

4

201

7

3 481

Diabetes mellitus,d

n (%)

234

(5.38)

3 153

(7.86)

126

(6.64)

81 890

(6.22)

161

1714

85

30 391

73

1439

41

51 499

Other cardiovascular disease,e n (%)

986

(22.69)

9 298

(23.19)

446

(23.50)

269 363

(20.47)

725

5403

324

119 658

261

3895

122

149 705

  1. Abbreviations: SED, chronic stress-induced exhaustion, DEP, depression
  2. aICD-10 code F00 Dementia in Alzheimer disease and G30 Alzheimer disease
  3. bICD-10 code F01 Vascular dementia, F02 Dementia in other diseases classified elsewhere, and F03 Unspecified dementia
  4. cICD-10 code F06.7 Mild cognitive impairment
  5. dICD-10 code E10 Type 1 diabetes mellitus, E11 Type 2 diabetes mellitus, and E14 Unspecified diabetes mellitus
  6. eICD-10 code I10 Essential (primary) hypertension, I11 Hypertensive heart disease, I12 Hypertensive renal disease, I13 Hypertensive heart and renal disease, I15 Secondary hypertension
  7. I20-25 Ischaemic heart diseases, I50 Heart failure, I60-69 Cerebrovascular diseases, and I73 Other peripheral vascular diseases