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Table 3 Association of Aβ positivity with cognitive trajectory

From: Independent effect of Aβ burden on cognitive impairment in patients with small subcortical infarction

 

Aβ effect

Time effect

Aβ positivity × time

Βa (95% CI)

p

Βa (95% CI)

p

Βa (95% CI)

p

K-MMSE

− 2.218 (− 4.568, 0.133)

0.064

− 0.654 (− 1.375, 0.068)

0.074

− 1.164 (− 2.488, 0.159)

0.083

CDR-SOB

0.998 (0.068, 1.929)

0.036

0.154 (− 0.207, 0.515)

0.393

0.846 (0.185, 1.508)

0.014

  1. Abbreviations: Aβ Amyloid-β, CDR-SOB Clinical Dementia Rating-Sum of Box, CI confidence interval, K-MMSE Korean version of the Mini-Mental Status Examination
  2. aΒ was obtained by a linear mixed-effect regression analysis with participant as a random effect and Aβ positivity, time, and Aβ positivity × time as fixed effects along with age, sex, education years, hypertension, diabetes, and WMH severity
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Alzheimer's Research & Therapy

ISSN: 1758-9193