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Fig. 3 | Alzheimer's Research & Therapy

Fig. 3

From: Performance of plasma Aβ42/40, measured using a fully automated immunoassay, across a broad patient population in identifying amyloid status

Fig. 3

The association between Centiloid and plasma Aβ42/40. a represents a scatterplot illustrating the relationship between CL and Aβ42/40. The vertical red and blue lines denote the established (CL = 35.7) and initial (CL = 13.5) amyloid pathology. The black horizontal line indicates the cut-off (0.0942) for plasma Aβ42/40. r denotes Spearman’s rank correlation coefficient. b is an enlarged view of the 'gray zone' within Fig. 3a. The black and red colors represent amyloid-negative and -positive determinations by plasma Aβ42/40, respectively. Circles and triangles represent amyloid-negative and -positive determinations by visual assessment of amyloid PET, respectively. Abbreviations: Aβ42/40 = amyloid β 42/40 ratio; CI = confidence interval, CL = Centiloid; PET = positron emission tomography

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