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Fig. 1 | Alzheimer's Research & Therapy

Fig. 1

From: Performance of plasma Aβ42/40, measured using a fully automated immunoassay, across a broad patient population in identifying amyloid status

Fig. 1

Four plasma biomarkers by visual assessment of amyloid PET. The red horizontal line denotes the Youden-Index-derived best cut-off value (0.0942). Black horizontal lines denote the median concentrations for each plasma biomarker. Differences in plasma biomarker values between Aβ negative and positive participants were analyzed using the Mann–Whitney U test. Abbreviations: Aβ42/40 = amyloid β 42/40 ratio; p-tau181 = tau protein phosphorylated at residue 181; GFAP = glial fibrillary acidic protein; NfL = neurofilament light. *** denotes p < 0.001, **** denotes p < 0.0001

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Alzheimer's Research & Therapy

ISSN: 1758-9193