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Fig. 7 | Alzheimer's Research & Therapy

Fig. 7

From: Feasibility and therapeutical potential of local intracerebral encapsulated cell biodelivery of BDNF to AppNL−G−F knock-in Alzheimer mice

Fig. 7

BDNF treatment effects on anxiety and spatial learning behavior in the AppNL−G−F mice. A Schematic representation of the study design in cohort 3. B BDNF release of ECBs at pre-implantation (pre-impl.) and after explantation (post-expl.) in cohort 3. C Three-month BDNF treatment effect on anxiety in mice using elevated plus maze (EPM), and D the spontaneous Y maze alternation in AppNL−G−F mice (n = 9–10). Data are represented as mean ± S.E.M. Data were analyzed by one-way ANOVA with Tukey’s multiple comparison test

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Alzheimer's Research & Therapy

ISSN: 1758-9193