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Fig. 5 | Alzheimer's Research & Therapy

Fig. 5

From: Feasibility and therapeutical potential of local intracerebral encapsulated cell biodelivery of BDNF to AppNL−G−F knock-in Alzheimer mice

Fig. 5

Immunofluorescence analysis revealed response to the implanted ECBs at 1-month post-surgery. Immunofluorescence intensity analysis of A, B BDNF release, C, D microglia (Iba1), E, F astrocytes (GFAP), G, H leukocytes (CD45), and I, J fibroblasts; in the proximity and distal area surrounding the ECB-BDNF devices in control (un-implanted) and ECB-BDNF implanted mice in cohort 1 (n = 2–4). Statistical comparison between groups were not applied due to the limited number of animals in control groups. Data represented as mean ± S.E.M

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Alzheimer's Research & Therapy

ISSN: 1758-9193