Table 1 Baseline characteristics between the groups

Female (n, %)

52 (59.8%)

7 (35.0%)

0.079

Age, years

69.77 ± 5.89

74.95 ± 5.72

0.001

Education, years

11.2 ± 4.1

13.2 ± 3.4

0.040

APOE4 carrier (n, %)

11 (12.6%)

10 (50.0%)

0.001

Waist circum, cm

87.1 ± 9.1

81.6 ± 9.2

0.015

Body fat (%)

29.8 ± 7.7

25.7 ± 8.7

0.037

Body muscle (%)

24.7 ± 6.7

23.7 ± 4.8

0.551

Visceral fat (%)

9.6 ± 3.6

6.5 ± 3.0

0.001

Global SUVR

1.198 ± 0.113

1.642 ± 0.202

 < 0.001

MDS_Plasma amyloid βeta

0.851 ± 0.199

0.961 ± 0.122

0.030

Deep WMH (mild/moderate/severe)

64/16/7

16/4/0

0.423

Periventricle WMH (mild/moderate/severe)

60/17/10

13/3/4

0.723

Lacunes (n)

0.09 ± 0.328

0.05 ± 0.224

0.589

Microbleed (n)

0.06 ± 0.234

0.15 ± 0.366

0.291

Framingham cardiovascular risk score

8.3 ± 6.9

12.7 ± 8.8

0.017

Baseline K-MMSE score

27.4 ± 1.9

26.9 ± 2.1

0.402

DST-Forward_percentile

63.1 ± 29.4

60.2 ± 32.3

0.691

K-BNT_percentile

60.6 ± 25.0

60.6 ± 32.9

0.995

RCFT Copy_percentile

58.5 ± 21.6

58.5 ± 22.2

0.992

SVLT delayed recall_percentile

30.0 ± 14.3

20.1 ± 12.5

0.005

RCFT delayed recall_percentile

48.5 ± 24.5

45.1 ± 25.3

0.572

Digit symbol constitution_score

63.4 ± 24.8

50.3 ± 34.0

0.051

COWAT phonemic_percentile

53.3 ± 28.0

55.2 ± 31.0

0.788

K-TMT-B_percentile

61.6 ± 22.2

61.8 ± 20.5

0.983

K-stroop color reading_percentile

56.0 ± 24.6

49.6 ± 29.8

0.317

K-ECOG memory total

17.7 ± 5.7

18.1 ± 4.9

0.819

K-ECOG total

72.1 ± 22.1

72.1 ± 20.5

0.999