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Fig. 2 | Alzheimer's Research & Therapy

Fig. 2

From: Plasma apolipoprotein E levels, isoform composition, and dimer profile in relation to plasma lipids in racially diverse patients with Alzheimer’s disease and mild cognitive impairment

Fig. 2

Distribution of APOE isoforms in the plasma. ApoE plasma isoform composition as a percentage of total apoE (a), plasma concentrations (b–d) of apoE2 (black dots), apoE3 (black triangles), and apoE4 (black squares) in APOE ε2/ε3 (b), APOE ε2/ε4 (c), and APOE ε3/ε4 (d) subjects. Data is presented % (a) and as medians- with lower and upper quartiles and whiskers indicating the data range (b-d). p-values illustrated in b and c were obtained using the Student’s t-test, whereas in d, both the Mann–Whitney U-test for the comparison in the combined races/ethnicities and Student’s t-test for the comparison in Black/African-Americans (B/AAs) and non-Hispanic whites (NHWs) were utilized. Comparison between apoE2 and apoE4 isoforms in APOE ε2/ε4 NHW could not be performed due to the low sample number (n = 1)

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Alzheimer's Research & Therapy

ISSN: 1758-9193