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Table 2 Correlations of plasma biomarkers of Alzheimer's disease with subject age

From: Reference intervals for plasma amyloid-β, total tau, and phosphorylated tau181 in healthy elderly Chinese individuals without cognitive impairment

Plasma biomarkers

Unadjusted

Adjusted

r

P value

r

P value

Aβ42

0.288

< 0.001

0.280

< 0.001

Aβ40

0.372

< 0.001

0.370

< 0.001

Aβ42/Aβ40 ratio

−0.204

0.014

-0.165

0.023

t-tau

0.027

0.746

0.053

0.462

p-tau181

0.292

< 0.001

0.305

< 0.001

p-tau181/t-tau ratio

0.156

0.033

0.141

0.053

p-tau181/Aβ42 ratio

0.145

0.081

0.084

0.250

  1. The plasma biomarkers concentrations were log transformed. The model was adjusted for gender, education year, and creatinine
  2. Abbreviations: Aβ Amyloid-beta protein, t-tau Total tau, p-tau181 Tau phosphorylated at threonine 181
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Alzheimer's Research & Therapy

ISSN: 1758-9193