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Fig. 1 | Alzheimer's Research & Therapy

Fig. 1

From: Shared genetic risk loci between Alzheimer’s disease and related dementias, Parkinson’s disease, and amyotrophic lateral sclerosis

Fig. 1

Genetic correlations between AD/ADRD, PD, and ALS according to three genetic correlation methods. Error bars indicate 95% confidence intervals. Single asterisks (*) indicate nominal significant genetic correlations (p < 0.05), while double asterisks (**) indicate genetic correlations significant after Bonferroni correction (p < 0.05/15). Note that ADRD and PD are slightly genetically correlated, while AD and PD are not, most likely due to the inclusion of non-AD dementias in the ADRD case definition (see the “Discussion” section)

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