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Table 2 Subcortical nuclei volumes (mm3)

From: Spatial navigation is associated with subcortical alterations and progression risk in subjective cognitive decline

 

NC (n = 77)

G-SCD (n = 40)

B-SCD (n = 40)

MCI (n = 23)

F

P

Basal forebrain

535.24 ± 40.62

539.47 ± 51.05

515.08 ± 42.47bd

499.95 ± 36.37ce

5.327

0.002*

L-Thalamus

5946.67 ± 563.92

5955.59 ± 650.65

5801.25 ± 580.15

5567.23 ± 414.48

2.262

0.083

L-Caudate

3077.73 ± 354.22

3176.93 ± 371.77

3065.99 ± 417.08

3084.21 ± 403.91

0.752

0.523

L-Putamen

4519.79 ± 448.30

4493.13 ± 518.10

4440.52 ± 554.15

4398.10 ± 347.17

0.224

0.879

L-Pallidum

1862.60 ± 240.92

1847.12 ± 219.02

1807.77 ± 254.06

1781.75 ± 262.65

0.396

0.756

L-Hippocampus

3577.23 ± 352.48

3576.78 ± 424.65

3484.67 ± 345.05

3312.63 ± 293.79

2.899

0.037

L-Amygdala

1359.26 ± 221.99

1281.10 ± 230.21

1301.93 ± 220.96

1232.48 ± 210.16

2.638

0.051

L-Accumbens

502.48 ± 87.68

493.19 ± 82.03

487.24 ± 77.49

448.04 ± 91.01

2.075

0.105

R-Thalamus

5813.13 ± 576.93

5757.73 ± 576.39

5667.74 ± 572.91

5498.96 ± 420.97

1.494

0.218

R-Caudate

3176.42 ± 349.43

3277.09 ± 376.46

3171.37 ± 415.60

3226.93 ± 493.72

0.879

0.453

R-Putamen

4503.70 ± 501.74

4494.81 ± 492.07

4466.18 ± 546.24

4406.74 ± 401.24

0.112

0.953

R-Pallidum

1757.02 ± 198.94

1784.53 ± 213.82

1754.38 ± 250.43

1702.58 ± 246.80

0.180

0.910

R-Hippocampus

3678.94 ± 379.55

3677.84 ± 450.97

3575.85 ± 407.17

3319.50 ± 345.14cef

4.693

0.004*

R-Amygdala

1534.93 ± 278.04

1484.69 ± 256.68

1474.44 ± 231.41

1358.29 ± 171.53

2.838

0.040

R-Accumbens

494.64 ± 81.59

489.63 ± 83.88

475.37 ± 66.99

454.74 ± 78.25

1.220

0.304

  1. Data were presented as means ± standard deviation
  2. L Left, R Right
  3. *p < 0.05, FDR corrected, controlling for sex, age, years of education, and total intracranial volume
  4. a~fPost hoc analyses showed a significant difference between groups. aNC vs G-SCD; bNC vs B-SCD; cNC vs MCI; dG-SCD vs B-SCD; eG-SCD vs MCI; fB-SCD vs MCI