Fig. 4
From: A peripheral signature of Alzheimer’s disease featuring microbiota-gut-brain axis markers
Association matrices of genera with MGBA mediators (A) and of the latter with amyloid cascade markers (B). Heatmap of the Spearman’s rho coefficient values (pink: positive; green: negative) indicating significant association (age adjusted, p < 0.05) in CU and CI-NAD or CU and CI-AD. The star indicates moderate associations (Spearman’s rho value > 0.4). For MMSE and ADAS-cog, higher values reflected higher cognitive scores. Abbreviations: CU, cognitively unimpaired persons; CI-NAD, patients with cognitive impairment not due to AD; CI-AD, patients with cognitive impairment due to AD