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Table 4 Test effects from multivariate linear regression models explaining regional 11C-PK11195 binding

From: APOE ε4 gene dose effect on imaging and blood biomarkers of neuroinflammation and beta-amyloid in cognitively unimpaired elderly

 

APOE ε4 gene dose

Aβ status

APOE ε4 gene dose ˟ Aβ status

F statistic

P

F statistic

P

F statistic

P

Anterior cingulum

0.034

0.97

1.21

0.28

0.0011

1.00

Posterior cingulum

0.10

0.90

0.001

0.97

2.11

0.13

Lateral temporal cortex

3.74

0.031

0.062

0.80

2.93

0.063

Parietal cortex

0.14

0.87

0.0053

0.94

1.75

0.18

Prefrontal cortex

1.14

0.33

0.0046

0.95

0.91

0.41

Precuneus

0.71

0.71

0.22

0.64

0.68

0.51

Cortical composite

0.98

0.38

0.022

0.88

2.54

0.089

Transentorhinal, Braak I–II

0.67

0.52

0.23

0.64

3.14

0.052

Limbic, Braak III–IV

1.05

0.36

0.035

0.85

4.28

0.019