Table 1 Demographics, clinical, and neuroimaging characteristics of the participants

n

41

35

34

60

Sex male/female, n

28/13^a

17/18^a

21/13^a

24/36^a

Race, white, n (%)

42 (100)^a

35 (100)^a

34 (100)^a

60 (100)^a

Education, years

15.1 (3.1)^a

15.8 (2.5)^a

15.9 (2.8)^a

16.5 (2.0)^a

Age at MRI, years

60.7 (6.3)^a

68.3 (7.4)^b

63.3 (6.3)^a

60.1 (7.9)^e

CDR® plus NACC FTLD-SB

9.4 (4.0)

4.3 (2.8)

5.9 (2.9)

-

CDR-BEHAV

1.7 (0.8)

0.5 (0.5)

1.1 (0.6)

-

CDR-LANG

0.9 (0.6)

1.4 (0.7)

1.0 (0.6)

-

Verbal Fluency Test (VFT)

-

 Verbal fluency—D words

5.0 (4.9)^c

5.1 (4.3)^c

7.8 (4.6)^de

-

 Verbal fluency—animals

8.1 (6.8)^a

8.3 (7.1)^a

7.9 (5.3)^a

-

 Boston Naming Test (BNT)

10.9 (4.6)^c

10.5 (5.1)^c

4.8 (3.5)^de

-

 CDR_SB

7.0 (3.2)^ce

2.3 (2.4)^d

3.8 (2.1)^d

-

Global CDR

-

 0.0 = no impairment, n (%)

5 (12.2)

6 (17.1)

2 (5.9)

-

 0.5 = questionable impairment, n (%)

19 (46.3)

20 (57.2)

9 (26.5)

-

 1.0 = mild impairment, n (%)

15 (36.6)

6 (17.1)

18 (52.9)

-

 2.0 = moderate impairment, n (%)

2 (4.9)

3 (8.6)

5 (14.7)

-

 eTIV, mL

1547.8 (169.8)^a

1473.3 (166.1)^a

1547.6 (154.6)^a

1474.5 (158.6)^a