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Table 1 Participant characteristics at baseline. Values reflect mean (SD) unless otherwise indicated

From: Alzheimer’s disease genetic risk and cognitive reserve in relationship to long-term cognitive trajectories among cognitively normal individuals

 

Participants in APOE analyses

Participants in AD-PRS analyses

N

1819

1175

Age at baseline cognitive assessment

63.90 (10.13)

62.54 (10.08)

Female sex, N (%)

1069 (59%)

711 (61%)

Years of education

14.99 (3.20)

15.89 (3.25)

CR index score

0.03 (0.83)

0.00 (0.84)

APOE-ε3 carriers, N (%)

1011 (56%)

668 (57%)

APOE-ε2 carriers, N (%)

226 (12%)

133 (11%)

APOE-ε4 carriers, N (%)

582 (32%)

374 (32%)

Global factor score

0.07 (0.95)

0.20 (0.92)

Episodic memory factor score a

0.02 (0.97)

0.09 (0.98)

Executive function factor score b

0.09 (0.91)

0.14 (0.88)

Number of cognitive scores over time

6.55 (4.13)

7.63 (3.84)

Years between baseline and last cognitive score [range]

9.85 (6.24) [0–28.8]

11.78 (5.17) [0–28.8]

  1. a N APOE analyses of memory factor score = 1813
  2. b N APOE analyses of executive function factor score = 1816