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Table 2 Group comparisons using log-transformed CSF-NfL and CSF-Ng concentrations in ATN groups in participants with global CDR0 (n=258)

From: Cerebrospinal fluid biomarkers of axonal and synaptic degeneration in a population-based sample

Neurofilament light (NfL)

Neurogranin (Ng)

ATN class

N

Mean (SD)

Cohen’s D

p

N

Mean (SD)

Cohen’s D

p

A−T−N− a

137

2.8 (0.2)

 

-

138

2.2 (0.1)

 

-

A−T−N+

49

3.0 (0.2)

1.0

0.001

49

2.4 (0.1)

2.0

<0.0001

A−T+N+

12

3.0 (0.03)

0.8

0.006

12

2.6 (0.1)

4.0

<0.0001

A+T−N−

32

2.9 (0.2)

0.5

0.509

33

2.2 (0.1)

0.0

0.107

A+T−N+

20

2.9 (0.2)

0.5

0.062

20

2.4 (0.1)

2.0

<0.0001

A+T+N+

6

3.0 (0.0)

1.4

0.125

6

2.5 (0.1)

3.0

<0.0001

  1. a A−T−N− was the reference group