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Table 3 Summary table of answers to the multiresponse question “what would make participation easier for you or others?”, stratified per diagnostic group

From: Experiences of and recommendations on clinical trial design in Alzheimer’s disease from the participant’s point of view: a mixed-methods study in two clinical trial centers in the Netherlands

What would make participation easier for you or others?

Overall

Alzheimer’s disease

Mild Cognitive impairment

Cognitively normal

N

% (ntotal=71)

n

% (nAD=33)

n

% (nMCI=19)

n

% (nCN=19)

Less chance to receive placebo

38

53.5%

18

54.5%

13

68.4%

7

36.8%

Shorter travel time

27

38.0%

14

42.4%

6

31.6%

7

36.8%

Less frequent lumbar puncture

22

31.0%

12

36.4%

4

21.1%

6

31.6%

Home visits

12

16.9%

9

27.3%

2

10.5%

1

5.3%

Less frequent visits to center

6

8.5%

5

15.2%

1

5.3%

0

0.0%

Study partner burden

9

12.7%

4

12.1%

1

5.3%

4

21.1%

Less frequent MRI scan

8

11.3%

3

9.1%

1

5.3%

4

21.1%

Less frequent PET scan

6

8.5%

3

9.1%

1

5.3%

2

10.5%

More compensation

5

7.0%

1

3.0%

4

21.1%

0

0%

Less frequent memory assessments

4

5.6%

2

6.1%

1

5.3%

1

5.3%

Less frequent depression assessments

2

2.8%

0

0%

2

10.5%

0

0%