From: Clinical features and biomarkers of semantic variant primary progressive aphasia with MAPT mutation
 | svPPA N=2 | Presymptomatic carriers N=7 | Noncarriers N=9 | P-value | |||||
---|---|---|---|---|---|---|---|---|---|
Representative subjects | III-12 | IV-22 | IV-2 | IV-30 | Mean (SD) | IV-32 | IV-33 | Mean (SD) | Â |
Spontaneous speech/100 | |||||||||
 Information content | 0 | 50 | 100 | 100 | 100 (0) | 100 | 100 | 100 (0) | ND |
 Fluency | 0 | 89 | 100 | 100 | 100 (0) | 100 | 100 | 100 (0) | ND |
 Repetition | 81 | 93 | 84 | 96 | 96 (6) | 100 | 98 | 97 (5) | 0.869 |
 Responsive naming | 50 | 60 | 100 | 100 | 100 (0) | 100 | 100 | 97 (10) | 0.396 |
Comprehension/100 | |||||||||
 Yes/no questions | 46 | 80 | 93 | 100 | 99 (3) | 100 | 100 | 96 (13) | 0.515 |
 Auditory word/picture matching | 62 | 82 | 94 | 97 | 100 (0) | 100 | 100 | 100 (0) | ND |
 Following directions | 45 | 79 | 100 | 100 | 100 (0) | 100 | 100 | 100 (0) | ND |
Reading/100 | |||||||||
 Oral reading | 80 | 80 | 100 | 100 | 100 (0) | 100 | 100 | 100 (0) | ND |
 Auditory word and print matching | 80 | 90 | 100 | 100 | 100 (0) | 100 | 100 | 100 (0) | ND |
 Reading and following written directions | 26 | 67 | 100 | 100 | 100 (0) | 100 | 100 | 98 (5) | 0.262 |
 Reading and filling in the blanks | 13 | 47 | 100 | 100 | 100 (0) | 100 | 100 | 100 (0) | ND |
Writing/100 | |||||||||
 Spontaneous writing | 0 | 100 | 100 | 100 | 97 (8) | 100 | 100 | 97 (8) | ND |
 Writing name and address | 100 | 100 | 100 | 100 | 100 (0) | 100 | 100 | 100 (0) | ND |
 Written naming of pictures | 20 | 70 | 100 | 100 | 100 (0) | 100 | 100 | 100 (0) | ND |
 Writing from dictation | 37.5 | 58 | 100 | 100 | 100 (0) | 100 | 100 | 100 (0) | ND |
 Copying | 100 | 100 | 100 | 100 | 100 (0) | 100 | 100 | 100 (0) | ND |