Fig. 4From: Clinical features and biomarkers of semantic variant primary progressive aphasia with MAPT mutationRegional CBF differences between mutation carriers and noncarriers. A Without adjusting for the global values, increased regional CBF was observed in mutation carriers. B After ANCOVA normalization to the global values, regions of relatively decreased and relatively increased regional CBF were both observed in the mutation carriers. A voxel-level peak threshold of P < 0.001 was used to overlay SPM maps onto a standard MRI brain template. Warm colours indicate regions with increased CBF in mutation carriers compared with noncarriers, while cold colours indicate regions with decreased CBFBack to article page