Diagnosis (baseline) | Healthy (Aβ−) | Cognitively normal (Aβ+) | Prodromal AD (Aβ+) | AD dementia (Aβ+) |
---|---|---|---|---|
N (baseline tau-PET, MRI) | 193 | 98 | 50 | 25 |
N (retrospective MRI) | 73 | 46 | 31 | 17 |
N (prospective MRI) | 66 | 57 | 42 | 13 |
Age at baseline (years) | 71.9 ± 6.4 [56, 95] | 75.5 ± 7.1 [62, 92]a | 75.3 ± 7.7 [59, 92]a | 78.2 ± 8.2 [56, 91]a |
Sex (% female) | 59.6 | 56.1 | 52 | 48 |
Education (years) | 17 ± 2.3 [11, 20]b | 16.7 ± 2.3 [12, 20]b | 15.6 ± 2.6 [12, 20] | 15.9 ± 2.6 [12, 20] |
APOE ε4 carriers (%)e | 23.6 | 56.7a | 62a | 56a |
MMSE at baselinef | 29.3 ± 1.0 [23, 30]c | 28.8 ± 1.5 [22, 30]c | 27.6 ± 2.3 [19, 30]d | 22 ± 4.2 [9, 30]d |