Skip to main content
Fig. 2 | Alzheimer's Research & Therapy

Fig. 2

From: Associations between different tau-PET patterns and longitudinal atrophy in the Alzheimer’s disease continuum: biological and methodological perspectives from disease heterogeneity

Fig. 2

Longitudinal changes in atrophy relative to baseline tau-PET patterns (continuous scale) in the AD continuum. Estimated longitudinal atrophy (thickness) estimated by linear mixed effects model for the entorhinal cortex and neocortex: A stratified by levels of typicality (the low/high groups were computed by median split in typicality); B stratified by levels of severity (the low/high groups were computed by median split in severity). Shaded regions represent the 95% confidence interval; percentages indicate the overall change in thickness per group over the period between retrospective and prospective timepoints; E:N = ratio of average entorhinal tau-PET SUVR to average neocortical tau-PET SUVR; SUVR = standardized uptake value ratio

Back to article page

Alzheimer's Research & Therapy

ISSN: 1758-9193