Early visual alterations in individuals at-risk of Alzheimer’s disease: a multidisciplinary approach

Table 4 Cluster-based permutation test for the relationships of TF activity with visual function and retinal thickness

	FH −			FH +			FH − _40-60ɛ4−			FH + _40-60ɛ4+
	n	rho	p	n	rho	p	n	rho	p	n	rho	p
Sensor space
VA	32	0.377	0.502	95	0.234	*0.005	14	0.488	0.604	27	0.450	*0.008
CS-3	30	0.382	0.550	91	0.202	0.469	14	0.596	0.118	27	0.360	0.095
CS-6	30	0.365	0.741	91	0.195	0.478	14	0.573	0.396	27	0.366	0.371
CS-12	30	0.337	0.893	91	0.191	0.435	14	0.568	0.840	27	0.361	0.092
CS-18	30	0.363	0.3321	91	0.215	0.205	14	0.486	0.679	27	0.476	*0.036
IPL-N1							13	0.624 − 0.653	1 1	21	0.514 − 0.480	1 1
IPL-N2							13	0.630 − 0.581	0.852 1	21	− 0.492	0.267
IPL-S1							13	0.616 − 0.641	1 1	21	0.500	0.351
IPL-I1							13	0.633 − 0.601	0.995 1	21	0.498 − 0.503	0.695 1
IPL-I2							13	− 0.647	1	21	− 0.487	0.203
INL-I2							13	0.636 − 0.602	0.428 1	20	− 0.542	1
Source space (Calcarine cortex)
VA	32	-	-	94	0.246	0.007	14	-	-	26	0.399	0.034
CS-3	30	-	-	90	-	-	14	0.470	0. 256	26	0.355	0.219
CS-6	30	-	-	90	-	-	14	0.527	0.200	26	0.336	0.290
CS-12	30	-	-	90	-	-	14	-	-	26	-	-
CS-18	30	0.331	0.202	90	-	-	14	-	-	26	0.436	0.028
IPL-N1							13	-	-	21	-	-
IPL-N2							13	-	-	21	-	-
IPL-S1							13	-	-	21	-	-
IPL-I1							13	-	-	21	− 0.458	0.183
IPL-I2							13	-	-	20	− 0.530	0.332
INL-I2							13	-	-	21	-	-

At the top, results in the sensor space. At the bottom, results in the source space, averaged in calcarine cortex following AAL atlas. Correlations with visual acuity and contrast sensitivity were left tailed contrasts, due to the theoretical hypotheses, while those with macular thickness were two-tailed. The differences in n with the original groups were due to invalid results in MEG or MRI. *p<0.05

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