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Table 2 Logistic regression analysis between the PSWEs and MCI in patients with OSA (n=275)

From: Paroxysmal slow wave events are associated with cognitive impairment in patients with obstructive sleep apnea

 

Model 0

Model 1

Model 2

OR (95%CIs)

P value

OR (95%CIs)

P value

OR (95%CIs)

P value

Total PSWEs

1.130 (1.026–1.244)

0.013

1.115 (1.009–1.231)

0.032

1.119 (1.007–1.245)

0.037

The PSWEs at C3/M2 in stage R

1.385 (0.973–1.973)

0.071

1.394 (0.975–1.993)

0.069

1.363 (0.944–1.969)

0.099

The PSWEs at C4/M1 in stage R

1.445 (1.008–2.072)

0.045

1.452 (1.009–2.090)

0.045

1.436 (0.985–2.095)

0.060

The PSWEs at F3/M2 in stage R

1.360 (0.950–1.948)

0.093

1.370 (0.952–1.973)

0.090

1.389 (0.951–2.027)

0.089

The PSWEs at F4/M1 in stage R

1.424 (1.006–2.016)

0.046

1.432 (1.005–2.039)

0.047

1.454 (1.006–2.098)

0.046

The PSWEs at O1/M2 in stage R

1.415 (1.055–1.900)

0.021

1.409 (1.043–1.902)

0.025

1.428 (1.041–1.959)

0.027

The PSWEs at O2/M1 in stage R

1.460 (1.091–1.954)

0.011

1.457 (1.082–1.962)

0.013

1.470 (1.076–2.010)

0.016

The PSWEs at T3/M2 in stage R

1.382 (0.942–2.027)

0.098

1.377 (0.933–2.032)

0.107

1.373 (0.918–2.053)

0.123

The PSWEs at T4/M1 in stage R

1.422 (0.981–2.062)

0.063

1.407 (0.964–2.053)

0.077

1.397 (0.944–2.069)

0.095

  1. Model 0: unadjusted
  2. Model 1: adjusted for age, sex, BMI, and education
  3. Model 2: adjusted for age, sex, education, vascular risk factors (e.g., hypertension, diabetes mellitus, hyperlipidemia), HAMD scores, Aβ42, and AHI
  4. Abbreviations: PSWE paroxysmal slow wave event, MCI mild cognitive impairment, OSA obstructive sleep apnea, OR odds ratio, CIs confidence interval, HAMD Hamilton Depression Scale, Aβ amyloid-β, AHI apnea-hypopnea index, R rapid eye movement