Fig. 2
From: Proteomic profiling of circulating plasma exosomes reveals novel biomarkers of Alzheimer’s disease
Heat map of 15 upregulated and 16 downregulated proteins in the pilot study (dataset 1). The heatmap was generated by log2 transformation of fold changes, with positive values representing upregulation (depicted in orange), and negative values representing downregulation (depicted in blue). AD, Alzheimer’s disease; A0A075B6R9, probable non-functional immunoglobulin kappa variable 2D-24; B1AHL2, fibulin-1; CC110, coiled-coil domain-containing protein 110; FCN2, ficolin-2;APOL1, apolipoprotein L1; HPTR, haptoglobin-related protein; KVD30, immunoglobulin kappa variable 2D-30; RSU1, Ras suppressor protein 1; GP1BB, platelet glycoprotein Ib beta chain; ALAT2, alanine aminotransferase 2; A0A0G2JRQ6, Ig-like domain-containing protein; CO9, complement component C9; C1QC, complement C1q subcomponent subunit C; CO7, complement component C7; CFAH, complement factor H; ADA10, disintegrin and metalloproteinase domain 10 (ADAM10); IGHA2, immunoglobulin heavy constant alpha 2; KT33A, keratin, type I cuticular Ha3-I; HV428, immunoglobulin heavy variable 4-28; HBB, hemoglobin subunit beta; A2MG, alpha-2-macroglobulin; A1AG2, alpha-1-acid glycoprotein 2; FA12, coagulation factor XII; IGHA1, immunoglobulin heavy constant alpha 1; KV315, immunoglobulin kappa variable 3-15; A0A087X1J7, glutathione peroxidase; AACT, alpha-1-antichymotrypsin; A0A1W2PR11, HLA class I histocompatibility antigen, C alpha chain; LV321, immunoglobulin lambda variable 3-21; HYDIN, hydrocephalus-inducing protein homolog; A0A087WXI2, IgGFc-binding protein