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Table 1 Participant characteristics by clinical diagnosis

From: Performance of a fully-automated Lumipulse plasma phospho-tau181 assay for Alzheimer’s disease

 

CU (n = 463)

MCI (n = 107)

AD (n = 78)

p value

Age, years

69.9 ± 7.8

73.0 ± 7.5a

70.1 ± 10.4b

0.0014

Sex, female

278 (60.0)

45 (42.0)

41 (52.6)

0.0026

Plasma p-tau181, pg/ml

1.68 ± 0.71

2.08 ± 0.74a

3.02 ± 1.16a,c

0.001

  1. Abbreviations: AD Alzheimer’s disease, CU clinically unimpaired, MCI mild cognitive impairment. Continuous variables expressed as mean ± SD while categorical values are expressed as n (%)
  2. a, *** vs CU; b, * vs MCI; c, *** vs. MCI. Data analyzed using one-way ANOVA with Tukey’s post hoc tests for multiple comparisons (age), chi-square (sex), or by ANCOVA with age and sex included as covariates (plasma p-tau181).* p < 0.05, *** p < 0.001
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Alzheimer's Research & Therapy

ISSN: 1758-9193